Noack J, Tönnies R, Hohla K, Birngruber R, Vogel A
Medizinisches Laserzentrum Lübeck GmbH, Germany.
Ophthalmology. 1997 May;104(5):823-30. doi: 10.1016/s0161-6420(97)30227-9.
The aim of this study was to understand the dynamics of ablation products during excimer laser photorefractive keratectomy, and their influence on the formation of central islands.
Laser flash photography was used to investigate the dynamics of ablation products during photorefractive keratectomy. The ablation plume over polymethyl methacrylate (PMMA) and porcine cornea targets ablated with different zone diameters was imaged at various times between 10 musec and 100 msec after the ablating laser pulse. On PMMA targets, the profiles of the resulting ablation craters were measured.
In all cases, the ablation products formed a ring vortex. The plume velocities on cornea were found to be approximately twice as fast as on PMMA for all zone diameters. For both materials, the ablation plume evolves faster for smaller zone diameters. Central islands were observed for zone diameters between 1 and 7 mm on PMMA substrates. The islands became more pronounced with increasing zone diameter.
A major cause for the formation of central islands was found to be particle redeposition at the center of the ablation zone. Because of the vortex dynamics, redeposition of particles favorably occurs at the center of the ablation zone. Additionally, the dynamics of the ablation plume lead to a concentration of airborne particles over the center of the ablation zone, which also may contribute to the creation of central islands by partial absorption of the next excimer laser pulse.
本研究旨在了解准分子激光屈光性角膜切削术中消融产物的动态变化及其对中央岛形成的影响。
采用激光闪光摄影术研究屈光性角膜切削术中消融产物的动态变化。在消融激光脉冲后的10微秒至100毫秒之间的不同时间,对用不同区域直径消融的聚甲基丙烯酸甲酯(PMMA)和猪角膜靶标的消融羽流进行成像。在PMMA靶标上,测量所得消融坑的轮廓。
在所有情况下,消融产物形成环形涡旋。发现对于所有区域直径,角膜上的羽流速度约为PMMA上的两倍。对于两种材料,较小区域直径的消融羽流演变更快。在PMMA基质上,观察到区域直径在1至7毫米之间出现中央岛。随着区域直径增加,这些岛变得更加明显。
发现中央岛形成的一个主要原因是颗粒在消融区中心的重新沉积。由于涡旋动力学,颗粒的重新沉积有利于在消融区中心发生。此外,消融羽流的动态变化导致消融区中心上方空气中颗粒的聚集,这也可能通过部分吸收下一个准分子激光脉冲而有助于中央岛的形成。