Charton-Bain M C, Le Tourneau A, Weiss L, Bruneval P, Diebold J
Service d'Anatomie Pathologique, Hôpital Broussais, Paris.
Ann Pathol. 1997 Mar;17(1):38-40.
Malignant non Hodgkin's lymphomas in patients with acquired immunodeficiency syndrome are usually of high grade and have a B-cell phenotype. We describe two cases of rare lymphomas during acquired immunodeficiency syndrome: one case of pleomorphic T cell lymphoma with medium and large cell predominance, of high grade of malignancy, according to the updated Kiel classification, involving mainly the bone-marrow, and one case of low grade monocytoid B-cell lymphoma with bone-marrow extension, which is a rare condition in this type of lymphoma. These lymphomas seem to be a casual event during acquired immunodeficiency syndrome, but the immunodeficiency can be responsible of a more aggressive behavior.
获得性免疫缺陷综合征患者的恶性非霍奇金淋巴瘤通常为高级别，且具有B细胞表型。我们描述了两例获得性免疫缺陷综合征期间罕见的淋巴瘤病例：一例为多形性T细胞淋巴瘤，以中、大细胞为主，根据更新的基尔分类为高级别恶性，主要累及骨髓；另一例为低级别单核细胞样B细胞淋巴瘤，伴有骨髓浸润，这在这类淋巴瘤中较为罕见。这些淋巴瘤似乎是获得性免疫缺陷综合征期间的偶发事件，但免疫缺陷可能导致更具侵袭性的行为。
