在按多重固定比率、反应间隔时间大于t的食物投递时间表进行操作的鸽子中，摇头丸和右旋苯丙胺产生类似的效果。
MDMA and d-amphetamine produce comparable effects in pigeons performing under a multiple fixed-ratio interresponse-time-greater-than-t schedule of food delivery.
作者信息
LeSage M, Poling A
机构信息
Department of Psychology, Western Michigan University, Kalamazoo 49008, USA.
出版信息
Pharmacol Biochem Behav. 1997 May-Jun;57(1-2):173-7. doi: 10.1016/s0091-3057(96)00302-4.
The purpose of this study was to gain further information about the behavioral effects of (+/-) 3.4-methylenedioxymethamphetamine (MDMA) on schedule-controlled responding. MDMA (0.32, 0.56, 1.0, 3.2, 5.6, and 10 mg/kg) and d-amphetamine (0.32, 0.56, 1.0, 3.2, 5.6, and 10 mg/kg) were administered to pigeons performing under a multiple fixed-ratio 30 (FR 30) interresponse-time-greater-than-15-s (IRT > 15-s) schedule of food delivery. In general, both drugs had no significant effect on response rates under the IRT > 15-s component at doses that decreased rates under the FR component. Results of the present experiment indicate that under some conditions MDMA and d-amphetamine produce similar, and rate-dependent, effects.
本研究的目的是获取更多关于（±）3,4-亚甲基二氧甲基苯丙胺（摇头丸）对按时间表控制的反应行为影响的信息。将摇头丸（0.32、0.56、1.0、3.2、5.6和10毫克/千克）和右旋苯丙胺（0.32、0.56、1.0、3.2、5.6和10毫克/千克）给予在多重固定比率30（FR 30）、反应间隔时间大于15秒（IRT>15秒）的食物递送时间表下进行操作的鸽子。一般来说，在降低FR部分反应率的剂量下，两种药物对IRT>15秒部分的反应率均无显著影响。本实验结果表明，在某些条件下，摇头丸和右旋苯丙胺会产生相似的、与速率相关的效应。
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