来自叙利亚仓鼠肾的谷胱甘肽S-转移酶Yc互补DNA

Glutathione S-transferase Yc cDNA from Syrian hamster kidney.

作者信息

Maggouta F, Li S A, Li J J, Norris J S

机构信息

Division of Rheumatology and Immunology, Medical University of South Carolina, 171 Ashley Avenue, Charleston, SC 29425, USA.

出版信息

Biochem J. 1997 Apr 1;323 ( Pt 1)(Pt 1):147-9. doi: 10.1042/bj3230147.

DOI:10.1042/bj3230147

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1218287/

Abstract

A cDNA encoding alpha-class glutathione S-transferase Yc (GSTYc) has been isolated from a Syrian hamster kidney library, and its nucleotide sequence (968 bp) has been determined. Analysis of the deduced amino acid sequence revealed a high level of identity between Syrian hamster GSTYc, rat GST Yc1 and Yc2 and mouse GSTYc. Northern-blot experiments demonstrated that Syrian hamster GSTYc expression is tissue-specific. A GSTYc mRNA of approx. 1 kb is expressed in liver, kidney, vas deferens and epididymis. Expression of the GSTYc transcript was not detected in testis or uterus.

摘要

已从叙利亚仓鼠肾文库中分离出编码α类谷胱甘肽S-转移酶Yc（GSTYc）的cDNA，并测定了其核苷酸序列（968 bp）。对推导的氨基酸序列进行分析发现，叙利亚仓鼠GSTYc、大鼠GST Yc1和Yc2以及小鼠GSTYc之间具有高度同源性。Northern印迹实验表明，叙利亚仓鼠GSTYc的表达具有组织特异性。约1 kb的GSTYc mRNA在肝脏、肾脏、输精管和附睾中表达。在睾丸或子宫中未检测到GSTYc转录本的表达。

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