Arnold W, Muresian T M, Kiricuta I, Graffi A
Oncology. 1977;34(4):156-8. doi: 10.1159/000225212.
It has been demonstrated by a syngeneic metastatic model of the XVII mouse that pretreatment of the animals with BCG and Freund's adjuvant brings about a significant inhibition of metastatic growth. This inhibition is further increased by combined pretreatment with nonspecific stimulants and additional specific immunisation of the animals against the given tumor.
通过XVII小鼠的同基因转移模型已证明,用卡介苗和弗氏佐剂对动物进行预处理可显著抑制转移瘤生长。通过与非特异性刺激剂联合预处理以及对动物针对特定肿瘤进行额外的特异性免疫,这种抑制作用会进一步增强。