Macknight R, Bancroft I, Page T, Lister C, Schmidt R, Love K, Westphal L, Murphy G, Sherson S, Cobbett C, Dean C
Department of Molecular Genetics, John Innes Centre, Norwich Research Park, Colney, United Kingdom.
Cell. 1997 May 30;89(5):737-45. doi: 10.1016/s0092-8674(00)80256-1.
A strong promoter of the transition to flowering in Arabidopsis is encoded by FCA. FCA has been cloned and shown to encode a protein containing two RNA-binding domains and a WW protein interaction domain. This suggests that FCA functions in the posttranscriptional regulation of transcripts involved in the flowering process. The FCA transcript is alternatively spliced with only one form encoding the entire FCA protein. Plants carrying the FCA gene fused to the strong constitutive 35S promoter flowered earlier, and the ratio and abundance of the different FCA transcripts were altered. Thus, FCA appears to be a component of a posttranscriptional cascade involved in the control of flowering time.
拟南芥中一个促进开花转变的强启动子由FCA编码。FCA已被克隆,并且显示其编码一种包含两个RNA结合结构域和一个WW蛋白相互作用结构域的蛋白质。这表明FCA在参与开花过程的转录本的转录后调控中发挥作用。FCA转录本可选择性剪接,只有一种形式编码完整的FCA蛋白。携带与强组成型35S启动子融合的FCA基因的植物开花更早,并且不同FCA转录本的比例和丰度发生了改变。因此,FCA似乎是参与开花时间控制的转录后级联反应的一个组成部分。