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[采用双主胰管转流及恢复胰头导管通畅性手术治疗以胰头受累为主的慢性胰腺炎]

[Surgical treatment of chronic pancreatitis with predominant cephalic involvement by double Wirsung duct diversion and restoration of permeability of the cephalic duct].

作者信息

Kestens P J, Gigot J F, Foxius A, Collard A, Gianello P

机构信息

Service de Chirurgie de I'Appareil Digestif, Cliniques Universitaires Saini-Luc, Bruxelles, Belgique.

出版信息

Ann Chir. 1996;50(10):853-60; discussion 861-4.

PMID:9183870
Abstract

The aim of this study is to assess the long-term results of an original surgical technique for the treatment of patients suffering from painful chronic pancreatitis. From 1981 to 1994, 54 patients with chronic painful pancreatitis were operated, by means of an original duct drainage procedure, named by the authors "double drainage" because it consists of a large transduodenal sphincterotomy and a long pancreatic duct, accompanied by repermeabilization of the cephalic pancreatic duct. This procedure was used exclusively for type I pancreatitis with major lesions in the head of the gland (calcified stones, narrowing of the ducts, inflammatory process). There were 40 men and 14 females in this series. No perioperative mortality and a low morbidity (22%) were observed. Mean follow-up in 52 patients was 56 months (median: 59.5 months). The 5- year actuarial survival was 85.2% and 81% were free of pain (91% when the pancreatic duct was dilated to > 6 mm) versus 63% when the pancreatic duct was (6 mm) (p < 0.01). These excellent results should serve as a baseline for any alternative treatment of this category of painful chronic pancreatitis patients.

摘要

本研究的目的是评估一种治疗疼痛性慢性胰腺炎患者的原创手术技术的长期效果。1981年至1994年,54例慢性疼痛性胰腺炎患者接受了手术,采用了一种原创的导管引流手术,作者将其命名为“双重引流”,因为它包括一个大的经十二指肠括约肌切开术和一条长的胰管,并伴有胰头导管再通。该手术仅用于I型胰腺炎,胰腺头部有主要病变(钙化结石、导管狭窄、炎症过程)。本系列中有40名男性和14名女性。未观察到围手术期死亡,发病率较低(22%)。52例患者的平均随访时间为56个月(中位数:59.5个月)。5年精算生存率为85.2%,81%的患者无疼痛(当胰管扩张至>6 mm时为91%),而当胰管为(6 mm)时为63%(p<0.01)。这些优异的结果应作为此类疼痛性慢性胰腺炎患者任何替代治疗的基线。

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