分化型甲状腺癌患者中不寻常的放射性碘全身扫描假阳性结果

Unusual false-positive radioiodine whole-body scans in patients with differentiated thyroid carcinoma.

作者信息

Salvatori M, Saletnich I, Rufini V, Troncone L

机构信息

Department of Nuclear Medicine, Catholic University of the Sacred Heart, Rome, Italy.

出版信息

Clin Nucl Med. 1997 Jun;22(6):380-4. doi: 10.1097/00003072-199706000-00007.

DOI:10.1097/00003072-199706000-00007

PMID:9193808

Abstract

Radioiodine whole-body imaging is the most accurate method in the diagnosis of metastases from differentiated thyroid cancer. However, false-positive images rarely occur. The authors report unusual cases of thymic hyperplasia and post-traumatic skull changes mimicking mediastinal, skull, or cerebral metastases. Nonthyroidal causes were diagnosed by other radionuclide studies (bone and brain scintigraphy) and CT scans. Follow-up and undetectable thyroglobulin levels helped confirm the benign cause.

摘要

放射性碘全身成像是诊断分化型甲状腺癌转移灶最准确的方法。然而，假阳性图像很少出现。作者报告了胸腺增生和创伤后颅骨改变酷似纵隔、颅骨或脑转移的不寻常病例。通过其他放射性核素检查（骨和脑闪烁扫描）及CT扫描诊断出非甲状腺原因。随访及不可检测的甲状腺球蛋白水平有助于证实良性病因。