Guner M M
Zh Nevropatol Psikhiatr Im S S Korsakova. 1977;77(9):1300-2.
The results of hemoglobin determination in the CSF by the method of fluorescence microscopy in 195 patients speaks in favor of relative diagnostical importance of hemoglobin in the supra fall-out CSF for establishing the character of the stroke. The following circumstances testify to this fact: 1) in an artificial admixture of blood in the CSF in some cases there may be hemolysis of "passing" erythrocytes; 2) in a genuine admixture of blood, tests of hemoglobin in the centrifugate of the CSF may be negative since in some cases the transition of hemoglobin into bilirubin in the subarachmoid space occurs more rapidly than the hemolysis of erythrocytes. Thus, the hemoglobin does not accumulate in the liquid in quantities, sufficient enough to be measured by the existing methods; 3) in a large amount of artificial blood admixture, even without a hemolysis of "passing" erythrocytes the hemoglobin tests in the centrifugate of the CSF may be positive at the expense of hemoglobin of the blood plasma.
通过荧光显微镜法对195例患者脑脊液中的血红蛋白进行测定的结果表明，在超沉降脑脊液中，血红蛋白对于确定中风的特征具有相对重要的诊断意义。以下情况证实了这一事实：1）在某些情况下，脑脊液中人工混入血液时，“路过”的红细胞可能会发生溶血；2）在真正的血液混入中，脑脊液离心液中的血红蛋白检测可能为阴性，因为在某些情况下，蛛网膜下腔中血红蛋白向胆红素的转化比红细胞溶血发生得更快。因此，血红蛋白不会在液体中大量积聚，不足以用现有方法进行测量；3）在大量人工混入血液的情况下，即使“路过”的红细胞没有发生溶血，脑脊液离心液中的血红蛋白检测也可能因血浆中的血红蛋白而呈阳性。
