Peach H G, Bath N E, Farish S
Ballarat Base Hospital Unit, Victoria, Australia.
Clin Lab Haematol. 1997 Jun;19(2):85-7. doi: 10.1046/j.1365-2257.1997.00055.x.
A recent study suggested that general practitioners (GPs) do not see the necessity of investigating MCVs which unexpectedly and only slightly exceed the reference limit, despite the association between MCV and alcohol abuse. Because a literature search could not find a study of the predictive value of the MCV for hazardous drinking in the community, such a study was undertaken among a random sample of 338 adults living in a regional Australian city. Twenty-nine of the adults admitted drinking hazardously. The MCV with the optimum sensitivity and specificity for identifying the hazardous drinkers was determined. An MCV of > 94 fl identified as many as 35% of the hazardous drinkers whilst misclassifying only 6% of the non-hazardous drinkers. The predictive value was even greater among males, 67%. We conclude that inquiring into MCVs > 94 fl will lead to GPs identifying a significant proportion of adults in the community admitting to hazardous drinking.
最近一项研究表明,尽管平均红细胞体积(MCV)与酗酒之间存在关联,但全科医生(GP)认为没有必要对意外且仅略高于参考值上限的MCV进行调查。由于文献检索未找到关于社区中MCV对危险饮酒预测价值的研究,因此在澳大利亚一个地区城市的338名成年人随机样本中开展了这样一项研究。其中29名成年人承认存在危险饮酒行为。确定了用于识别危险饮酒者的具有最佳敏感性和特异性的MCV。MCV大于94飞升可识别多达35%的危险饮酒者,同时仅将6%的非危险饮酒者误分类。在男性中预测价值更高,为67%。我们得出结论,询问MCV大于94飞升将使全科医生识别出社区中相当比例承认危险饮酒的成年人。