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下腹部手术后硬膜外镇痛对呼吸的影响。

Respiratory effects of extradural analgesia after lower abdominal surgery.

作者信息

Drummond G B, Littlewood D G

出版信息

Br J Anaesth. 1977 Oct;49(10):999-1004. doi: 10.1093/bja/49.10.999.

Abstract

Blood-gas tensions, FRC and volume of trapped gas (VTG) in the lung were measured in patients on the day before lower abdominal gynaecological surgery, and twice on the day following surgery, before and after establishing lumbar extradural block (EDB) using 0.5% bupivacaine to provide analgesia after operation. FRC and VTG were measured with the closed-circuit helium-dilution technique. Mean VTG was 175 ml before operation and 275 ml after operation. PaO2 decreased significantly after operation, and the changes in FRC and VTG that occurred were related qualitatively. EDB did not significantly alter FRC, VTG or PaO2. Individual changes in FRC could not be related to changes in VTG or PaO2. Although EDB provided effective analgesia, the variables measured did not indicate that EDB conferred an immediate respiratory advantage.

摘要

在下腹妇科手术前一天,对患者进行了血气张力、功能残气量(FRC)和肺内潴留气体量(VTG)的测量,并在术后当天使用0.5%布比卡因建立腰段硬膜外阻滞(EDB)以提供术后镇痛前后各测量了两次。FRC和VTG采用闭路氦稀释技术进行测量。术前平均VTG为175ml,术后为275ml。术后PaO₂显著下降,FRC和VTG的变化在性质上相关。EDB并未显著改变FRC、VTG或PaO₂。FRC的个体变化与VTG或PaO₂的变化无关。尽管EDB提供了有效的镇痛,但所测量的变量并未表明EDB带来了即时的呼吸优势。

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