Davidović L B, Lotina S I, Kostić D M, Cinara I I, Cvetković S D, Stojanović P L, Velimirović L B, Marković D M, Pejkić S L, Pavlović G
Centre for Vascular Surgery, Serbian Clinical Centre, Belgrade.
Srp Arh Celok Lek. 1997 Mar-Apr;125(3-4):75-83.
In reconstructive procedures of the abdominal aorta synthetic grafts are today mostly used. There are two types of bifurcated synthetic grafts: Dacron and polytetrafluorethilene (PTFE). In many papers these grafts are compared in aortobifemoral position. Karner 1988, and Lord 1988, found no significant difference between them after aortobifemoral reconstructions. In 1955. Paaske wrote about a new "stretch" bifurcated PTFE graft in aortobifemoral position. Comparing this material with standard Dacron graft, he only found a shorter operating time. The aim of this paper is to compare Dacron and PTFE bifurcated grafts in aortobifemoral position in patients with aortoiliac occlusive diseases.
This prospective study included 283 aortobifemoral reconstructions due to aortoiliac occlusive diseases operated between January 1st, 1984 and December 31st, 1992 at the Institute for Cardiovascular Diseases of the Serbian Clinical Centre in Belgrade. Bifurcated PTFE grafts were used in 136 patients, and nonimpregnated knitted Dacron grafts in 147 subjects. There were 25 (8.8%) female and 258 (91.2%) male patients, average age 56.88 years. Ninety one (32.2%) patients had a claudication discomfort (Fonten stadium II), 91 (32.2%) disabling claudication discomfort (Fonten stadium IIB), 45 (15.9%) rest pain (Fonten stadium III), and 56 (19.8%) gangrene (Fonten stadium IV). In 45 (15.9%) patients previous vascular procedures were performed. Prior to operation, Doppler ultrasonography and translumbar aortography were carried out (Figure 1). Transperitoneal approach to abdominal aorta, and standard inguinal approach to femoral arteries were used. In 154 (54.4%) patients proximal anastomosis had an end to side (TL), and in 129 (45.6%) end to end (TT) form. In 152 (26.88%) cases distal anastomosis was done in the common femoral (AFC) artery, and in 414 (73.2%) cases in the deep femoral (APF) artery. In 7 patients the aorto-femoro-popliteal "jumping" bypass was done, and in 29 patients simultaneous sequential femoro-popliteal bypass graft. The patients were following-up over the period from one, six and twelve months after operation, and later once a year, using physical examination and Doppler ultrasonography. In patients with suspected graft occlusion, anastomotic stenosis, pseudoaneurysms, progression of distal arterial diseases, Duplex ultrasonography and angiography were also used, and leukoscintigraphy in patients with suspected infection. Statistical analysis was performed using Long Rank and Student t-test.
Inhospital mortality rate was 11 (7%). Distal reconstructions significantly increased the mortality rate when simultaneously performed with aortobifemoral bypass graft (p < 0.01). The follow-up period was from 2 months to 9.5 years (mean 3.6 years). The early patency rate was 97% from PTFE and 99.4% for Dacron grafts, while the late patency rate was 94.9% for PTFE and 96.6% for Dacron grafts. The type of the graft had no statistical influence on the early and late graft patency (p > 0.05) (Graphs 1, 2, 3). Six (2.1%) early unilateral limb occlusions were observed. Five patients had the PTFE and one the Dacron graft, without statistically significant difference (p > 0.05). The reasons for early graft occlusion were: stenosis of distal anastomosis in 3 patients, and pure run off in 3 patients. In 5 patients urgent reoperation (limb thrombectomy with profundoplasty or femoro-popliteal bypass graft above the knee) were done with complete recovery of legs. However, in one patient the above knee amputation was done. During the follow-up period, 14 (5.2%) late graft occlusions were recorded. There were 11 unilateral limb occlusions and 3 bilateral. All patients with bilateral occlusions had PTFE grafts but this was not statistically significant (p > 0.05) comparing two types of grafts. Taking into account all late occlusions, there were 7 PTFE and 7 Dacron grafts. There was no statistical difference betwe
在腹主动脉重建手术中,如今大多使用合成移植物。有两种分叉型合成移植物:涤纶和聚四氟乙烯(PTFE)。在许多论文中,这些移植物在主动脉双股位置进行了比较。1988年的卡纳和1988年的洛德发现,在主动脉双股重建术后,它们之间没有显著差异。1955年,帕斯克报道了一种新的“可拉伸”分叉型PTFE移植物用于主动脉双股位置。将这种材料与标准涤纶移植物进行比较时,他只发现手术时间更短。本文的目的是比较涤纶和PTFE分叉型移植物在主髂动脉闭塞性疾病患者的主动脉双股位置的情况。
这项前瞻性研究纳入了1984年1月1日至1992年12月31日在贝尔格莱德塞尔维亚临床中心心血管疾病研究所因主髂动脉闭塞性疾病接受手术的283例主动脉双股重建患者。136例患者使用了分叉型PTFE移植物,147例患者使用了未浸渍的针织涤纶移植物。有25名(8.8%)女性和258名(91.2%)男性患者,平均年龄56.88岁。91名(32.2%)患者有间歇性跛行不适(Fonten分期II),91名(32.2%)有致残性间歇性跛行不适(Fonten分期IIB),45名(15.9%)有静息痛(Fonten分期III),56名(19.8%)有坏疽(Fonten分期IV)。45名(15.9%)患者此前接受过血管手术。术前进行了多普勒超声检查和经腰主动脉造影(图1)。采用经腹途径处理腹主动脉,采用标准腹股沟途径处理股动脉。154名(54.4%)患者近端吻合采用端侧(TL)方式,并129名(45.6%)采用端端(TT)方式。152例(26.88%)远端吻合在股总动脉(AFC)进行,414例(73.2%)在股深动脉(APF)进行。7例患者进行了主动脉 - 股 - 腘“跳跃”旁路手术,29例患者同时进行了序贯股 - 腘旁路移植。术后1个月、6个月和12个月对患者进行随访,之后每年随访一次,采用体格检查和多普勒超声检查。对于怀疑移植物闭塞、吻合口狭窄、假性动脉瘤、远端动脉疾病进展的患者,还使用了双功超声检查和血管造影,对于怀疑感染的患者使用了白细胞闪烁扫描。使用长秩检验和学生t检验进行统计分析。
住院死亡率为11例(7%)。当与主动脉双股旁路移植同时进行远端重建时,死亡率显著增加(p < 0.01)。随访期为2个月至9.5年(平均3.6年)。PTFE移植物的早期通畅率为97%,涤纶移植物为99.4%,而PTFE移植物的晚期通畅率为9