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老年患者的死因:一项跨文化研究。

Causes of death in geriatric patients: a cross-cultural study.

作者信息

Klima M P, Povysil C, Teasdale T A

机构信息

Veterans Affairs Medical Center, Houston, Texas., USA.

出版信息

J Gerontol A Biol Sci Med Sci. 1997 Jul;52(4):M247-53. doi: 10.1093/gerona/52a.4.m247.

Abstract

BACKGROUND

The elderly are living longer and causes of death are shifting. At the same time, autopsy rate is at, or near, its lowest in history, compounded by an even lower interest in geriatric autopsies. Thus, the prevalent cause of death in this age group remains poorly studied.

METHODS

In a retrospective study, the autopsy protocols of 440 70-year-old or older patients from the Houston Veterans Affairs Hospital and 321 80-year-old or older patients from the II*Institute of Pathology in Prague (Czech Republic) were reviewed in order to establish a correct cause of death. The autopsy diagnosis was correlated with the prosectors' description of pathological findings in the protocol. In questionable cases or discrepancies, the patient's clinical chart and/or the histological autopsy slides were also reviewed.

RESULTS

The distribution of death by infections and cardiac disorders each accounted for one-third of all deaths. Congestive heart failure prevailed in the over 80-year-olds, and myocardial infarcts prevailed in the younger patients. The number of deaths due to malignancy dropped from 25% in those 70-79 years old to about 10% in the elder patients. Central nervous system disorders were frequent as an underlying disease, but were not common as a cause of death. The findings were similar in both series, thus supporting their accuracy.

CONCLUSION

Our findings bring into question the accuracy of reported causes of death in the elderly. With increasing age, differences appear in the levels of mortality and morbidity for various disease categories. This study underlines the need for more baseline data for older people which can be obtained only by more and well-performed autopsies.

摘要

背景

老年人寿命延长,死亡原因正在发生变化。与此同时,尸检率处于或接近历史最低水平,而老年尸检的关注度更低。因此,这个年龄组中普遍的死亡原因仍未得到充分研究。

方法

在一项回顾性研究中,对来自休斯顿退伍军人事务医院的440名70岁及以上患者以及来自布拉格(捷克共和国)第二病理研究所的321名80岁及以上患者的尸检记录进行了审查,以确定正确的死亡原因。尸检诊断与记录中病理学家对病理结果的描述相关。在有疑问的病例或存在差异的情况下,还会查阅患者的临床病历和/或组织学尸检切片。

结果

感染和心脏疾病导致的死亡各占所有死亡人数的三分之一。充血性心力衰竭在80岁以上人群中更为常见,而心肌梗死在年轻患者中更为常见。因恶性肿瘤导致的死亡人数从70 - 79岁人群中的25%降至老年患者中的约10%。中枢神经系统疾病作为潜在疾病较为常见,但作为死亡原因并不常见。两个系列的结果相似,从而支持了其准确性。

结论

我们的研究结果对老年人报告的死亡原因的准确性提出了质疑。随着年龄的增长,不同疾病类别的死亡率和发病率出现差异。本研究强调需要更多针对老年人的基线数据,而这只能通过更多且高质量的尸检来获得。

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