Skriabin O N, Korobchenko A A, Lobach S M, Musinov I M
Vestn Khir Im I I Grek. 1997;156(2):35-7; discussion 38-9.
The frequency of acute sources of bleeding has recently increased (47%) in the general picture of gastrointestinal bleedings which makes the improvement of diagnosing "acute" sources of hemorrhage and the development of more perfect methods of nonoperative hemostasis very actual. The authors believe that "Kaprofer" used in most of patients with bleedings from acute ulcers and ruptures of the gastro-esophageal zone mucosa (95%) allows the hemorrhage to be arrested. The treatment can be continued without operative interventions. Search for new hemostatic drugs must be performed in order to obtain reliable and long-term effects of drugs with a minimum aggressive action upon the mucosa.
在胃肠道出血的总体情况中,急性出血源的发生率最近有所上升(47%),这使得改进“急性”出血源的诊断以及开发更完善的非手术止血方法变得非常迫切。作者认为,大多数患有急性溃疡和胃食管区黏膜破裂出血的患者(95%)使用“卡普罗费尔”可使出血停止。治疗可以在不进行手术干预的情况下继续进行。必须寻找新的止血药物,以便获得对黏膜侵袭作用最小的药物的可靠且长期的效果。