Leisure G P, Vesselle H J, Faulhaber P F, O'Donnell J K, Adler L P, Miraldi F
PET Facility, University Hospitals of Cleveland, Case Western Reserve University, School of Medicine, Ohio, USA.
J Nucl Med Technol. 1997 Jun;25(2):115-9.
PET tumor imaging of the abdomen and pelvis is prone to artifacts due to urinary tract activity. A new technique has been developed to reduce such artifacts and enhance study interpretation.
Thirty minutes after the injection of 18F-FDG, 500 cc 0.45% NaCl were administered intravenously over 30 min and a Foley catheter was placed in the bladder. At the start of imaging (60 min post-injection), furosemide was given (0.3 mg/kg). Prior to imaging the pelvis, the urinary catheter was clamped and saline was introduced retrograde into the bladder until full.
This technique has been used successfully in more than 130 patients, resulting in a marked improvement in study quality and tumor detection.
Hydration and administration of furosemide, along with placement of a Foley catheter in the bladder, have proven effective in eliminating image artifacts originating from the kidneys, ureters and bladder. Backfilling the bladder also provides a well-defined anatomic landmark for study interpretation.
由于泌尿道活动,腹部和盆腔的PET肿瘤成像容易出现伪影。已开发出一种新技术来减少此类伪影并增强研究解读。
注射18F-FDG 30分钟后,在30分钟内静脉注射500 cc 0.45%氯化钠,并在膀胱中放置一根Foley导管。在成像开始时(注射后60分钟),给予呋塞米(0.3 mg/kg)。在对盆腔进行成像之前,夹住导尿管并将盐水逆行注入膀胱直至充满。
该技术已在130多名患者中成功使用,显著提高了研究质量和肿瘤检测率。
水化、给予呋塞米以及在膀胱中放置Foley导管已被证明可有效消除源自肾脏、输尿管和膀胱的图像伪影。膀胱回填还为研究解读提供了明确的解剖标志。