[Effect of patients' gender on the course of chronic myeloid leukemia].
作者信息
Abdulkadyrov K M, Rukavitzyn O A, Bessmel'tsev S S, Lomtev A Iu
出版信息
Vopr Onkol. 1997;43(3):290-4.
PMID:9245084
Abstract
Chronic myeloid leukemia course was evaluated versus sex in 271 patients. Chronic stage involved more pronounced leukocytosis, thrombocytosis and splenomegaly in females, the latter showing higher susceptibility to anemia. As a result, treatment has to deal with a greater mass of tumor. A relatively longer survival time in males (44 and 42 months, respectively) suggest a higher effectiveness of therapy in such patients. When diagnosed, leukocytosis, thrombocytosis, enhanced splenomegaly and anemia should be regarded as factors of unfavorable prognosis.
摘要
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