尿液中三甲胺的1H-NMR分析用于鱼腥味综合征的诊断。

1H-NMR analysis of trimethylamine in urine for the diagnosis of fish-odour syndrome.

作者信息

Maschke S, Wahl A, Azaroual N, Boulet O, Crunelle V, Imbenotte M, Foulard M, Vermeersch G, Lhermitte M

机构信息

Laboratoire de Biochimie, Hôpital Calmette, CHR et U de Lille, France.

出版信息

Clin Chim Acta. 1997 Jul 25;263(2):139-46. doi: 10.1016/s0009-8981(97)00060-0.

DOI:10.1016/s0009-8981(97)00060-0

PMID:9246418

Abstract

This paper reports the use of proton NMR spectroscopy for the analysis of trimethylamine in the urine of a patient with trimethylaminuria. Analysis of this compound was also performed for other members of his family. Qualitative and quantitative determination of trimethylamine and trimethylamine-N-oxide was simultaneously performed on untreated urine within a few minutes. The application of the method is discussed.

摘要

本文报道了利用质子核磁共振波谱法分析一名三甲胺尿症患者尿液中的三甲胺。还对其家族的其他成员进行了该化合物的分析。在几分钟内对未经处理的尿液同时进行了三甲胺和三甲胺 - N - 氧化物的定性和定量测定。并对该方法的应用进行了讨论。