Kamble R, Kochupillai V, Sharma A, Kumar L, Thulkar S, Sharma M C, Mittal S
Department of Medical Oncology, Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.
J Obstet Gynaecol Res. 1997 Jun;23(3):261-6. doi: 10.1111/j.1447-0756.1997.tb00842.x.
Localized extramedullary collection of leukemic cells is termed as granulocytic sarcoma. Incidences of 2-8% in acute myeloid leukemia have been reported in various autopsy studies. In female it usually involves ovary. Since most of such tumors are asymptomatic, they are detected only at autopsy. We report here a case who manifested as abnormal vaginal bleeding, large cervical mass, renal failure, and aspergillous fungaemia. The patient died before she could be treated. From the present report it would appear that granulocytic sarcoma at times may precede other manifestations of leukemia.
白血病细胞的局限性髓外聚集称为粒细胞肉瘤。在各种尸检研究中,急性髓系白血病的发病率报告为2%-8%。在女性中,它通常累及卵巢。由于大多数此类肿瘤无症状,仅在尸检时才被发现。我们在此报告一例表现为异常阴道出血、巨大宫颈肿块、肾衰竭和曲霉菌血症的病例。患者在接受治疗前死亡。从本报告来看,粒细胞肉瘤有时可能先于白血病的其他表现出现。