梅毒螺旋体烯醇酶基因的核苷酸序列。

Nucleotide sequence of the Treponema pallidum eno gene.

作者信息

Stamm L V, Young N R

机构信息

Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill 27599-7400, USA.

出版信息

DNA Seq. 1997;7(5):261-5. doi: 10.3109/10425179709034045.

DOI:10.3109/10425179709034045

PMID:9255517

Abstract

We determined the nucleotide sequence of the enolase (eno) gene of Treponema pallidum, the noncultivable agent of syphilis. The deduced amino acid sequence of T. pallidum enolase (Eno) is 432 amino acids long with a predicted molecular mass of 46.7 kDa. The Eno amino acid sequence has a high degree of homology to the amino acid sequences of prokaryotic and eukaryotic Eno. This is the first eno sequence reported for a bacterium in the order Spirochaetales.

摘要

我们测定了梅毒的不可培养病原体梅毒螺旋体烯醇化酶（eno）基因的核苷酸序列。梅毒螺旋体烯醇化酶（Eno）推导的氨基酸序列长度为432个氨基酸，预测分子量为46.7 kDa。Eno氨基酸序列与原核和真核Eno的氨基酸序列具有高度同源性。这是螺旋体目细菌中首次报道的eno序列。