Yasui T, Sakamoto H, Kishi H, Komiyama M, Iwai Y, Yamanaka K, Nishikawa M, Nakajima H
Osaka City General Hospital, Department of Neurosurgery.
No Shinkei Geka. 1997 Aug;25(8):755-62.
The authors report four cases of patients with documented asymptomatic intact aneurysms that subsequently ruptured. Case 1 involves a 64-year-old woman who had two unruptured aneurysms, i.e., an anterior communicating artery aneurysm and a posterior inferior cerebellar aneurysm, both were discovered during evaluation of cerebral ischemic symptoms. At that time, only the posterior inferior cerebellar aneurysm was clipped. Seven years later, the patient bled fatally from a 5-mm untreated anterior communicating artery aneurysm that had measured approximately 3 mm on an angiogram obtained 7 years earlier. Case 2 is that of a 50-year-old woman who bled from an anterior communicating artery aneurysm that had been discovered 6 years earlier when she suffered subarachnoid hemorrhage (SAH) from a left middle cerebral artery aneurysm. At that time, she had refused surgery for the anterior communicating artery aneurysm. She recovered well from the second SAH. Case 3 is that of a 74-year-old woman who bled from a left paraclinoid internal carotid artery aneurysm that had been discovered incidentally 3 years earlier during evaluation of vertigo. She had not agreed to have a clipping at that time the aneurysm was first discovered because of her age and the difficult location of the aneurysm. She eventually made an uneventful recovery. In the fourth case, during evaluation of cerebral ischemic symptoms, a 59-year-old man was discovered to have a large basilar bifurcation aneurysm. He underwent a craniotomy for clipping of the aneurysm. The aneurysm, however, was unclippable and was instead coated with Bemsheet. Four months later, the patient bled from the aneurysm and entered a vegetative state. The indications for surgery on unruptured asymptomatic cerebral aneurysms are still unclear. The cases reported herein show that asymptomatic aneurysms, especially anterior communicating aneurysms and aneurysms once exposed surgically, do carry a certain risk for future hemorrhage and should not be dismissed as innocuous. Neurosurgeons have recognized the importance of considering life expectancy in managing patients with asymptomatic, unruptured, intracranial aneurysms. With the rapid aging of the population, withholding aneurysm surgery merely because a patient is elderly may not necessarily be the most appropriate decision.
作者报告了4例有记录的无症状完整动脉瘤随后破裂的病例。病例1为一名64岁女性,她有两个未破裂的动脉瘤,即前交通动脉瘤和小脑后下动脉瘤,均在评估脑缺血症状时被发现。当时,仅对小脑后下动脉瘤进行了夹闭术。7年后,患者因一个5毫米未治疗的前交通动脉瘤破裂而致命,该动脉瘤在7年前的血管造影中测量约为3毫米。病例2是一名50岁女性,她因前交通动脉瘤破裂出血,该动脉瘤6年前在她因左大脑中动脉瘤发生蛛网膜下腔出血(SAH)时被发现。当时,她拒绝了前交通动脉瘤的手术治疗。她从第二次SAH中恢复良好。病例3是一名74岁女性,她因左床突旁颈内动脉瘤破裂出血,该动脉瘤3年前在评估眩晕时偶然被发现。由于她的年龄和动脉瘤位置困难,在首次发现动脉瘤时她不同意进行夹闭术。她最终顺利康复。在第四例中,在评估脑缺血症状时,一名59岁男性被发现有一个大型基底动脉分叉动脉瘤。他接受了开颅夹闭动脉瘤手术。然而,该动脉瘤无法夹闭,而是用Bemsheet覆盖。4个月后,患者因动脉瘤破裂出血并进入植物人状态。无症状未破裂脑动脉瘤的手术指征仍不明确。本文报告的病例表明,无症状动脉瘤,尤其是前交通动脉瘤和曾经接受过手术暴露的动脉瘤,确实存在未来出血的一定风险,不应被视为无害。神经外科医生已经认识到在管理无症状、未破裂的颅内动脉瘤患者时考虑预期寿命的重要性。随着人口的快速老龄化,仅仅因为患者年龄大而不进行动脉瘤手术不一定是最合适的决定。