Jørgensen P, Bennedsen B, Christensen J, Hyllested A
Department A, Psychiatric Hospital, Risskov, Denmark.
Acta Psychiatr Scand. 1997 Aug;96(2):150-4. doi: 10.1111/j.1600-0447.1997.tb09920.x.
A study sample consisting of 51 patients suffering from acute and transient psychotic disorder (ATPD) (ICD-10) on initial examination was evaluated at 1-year follow-up. The findings show a diagnostic change in half of the patients (48%), most often to schizophrenia (15%) and affective disorder (28%). From index admission to follow-up, patients with an unchanged diagnosis of ATPD manage fairly well with regard to psychosocial functioning, and no deteriorating development is observed. In the majority of cases no personality disorder (PD) (ICD-10, 54%; DSM-IV, 71%) is apparent, and the ATPD is not related to any specific PD. With regard to diagnostic stability, no significant demographic, social or clinical predictors were found. The findings highlight the need for validation of the concept of ATPD, and point to the fact that brief psychotic episodes with an acute onset may be an early manifestation of severe mental disorder (schizophrenia and affective disorder).
一项针对51例初诊为急性短暂性精神病性障碍(ATPD,国际疾病分类第10版)患者的研究样本进行了为期1年的随访评估。研究结果显示,半数患者(48%)出现了诊断变化,最常见的是转变为精神分裂症(15%)和情感障碍(28%)。从首次入院到随访期间,诊断未变的ATPD患者在心理社会功能方面表现良好,未观察到病情恶化。在大多数病例中,未发现明显的人格障碍(ICD - 10为54%,DSM - Ⅳ为71%),且ATPD与任何特定人格障碍均无关联。关于诊断稳定性,未发现显著的人口统计学、社会或临床预测因素。这些研究结果凸显了对ATPD概念进行验证的必要性,并指出急性起病的短暂精神病性发作可能是严重精神障碍(精神分裂症和情感障碍)的早期表现。