Murris-Espin M, Lacassagne L, Didier A, Voigt J J, Cisterne J M, Giron J, Durand D, Leophonte P
Service de Pneumologie-Allergologie, Hôpital de Rangueil, Toulouse, France.
Eur Respir J. 1997 Aug;10(8):1925-7. doi: 10.1183/09031936.97.10081925.
Metastatic pulmonary calcifications, unlike dystrophic calcifications, occur in the normal healthy lung. The radiological pattern is quite specific. The disease is commonly described in chronic renal failure with calcium disorders. The prognosis is totally unpredictable. In 1992, a 50 yr old man underwent a successful renal transplantation during the final stage of chronic renal failure. He subsequently developed asymptomatic diffuse nodular opacities, that were discovered in 1995. An open lung biopsy confirmed the diagnosis of metastatic pulmonary calcification. There was no calcium disorder in this patient. In contrast to the benign course of pulmonary calcification in most patients, some fulminant pulmonary calcifications complicating renal transplantation or hypercalcaemia have been described. Radiographic identification of such entities is important to permit correction of calcium disorders. Otherwise, the condition is a potentially progressive and fatal cause of respiratory failure.
转移性肺钙化与营养不良性钙化不同，发生于正常健康的肺脏。其影像学表现颇为特异。该病常见于伴有钙代谢紊乱的慢性肾衰竭患者。预后完全不可预测。1992年，一名50岁男性在慢性肾衰竭终末期接受了成功的肾移植手术。随后，他于1995年被发现出现了无症状的弥漫性结节状混浊。开胸肺活检确诊为转移性肺钙化。该患者并无钙代谢紊乱。与大多数患者肺钙化的良性病程不同，已有一些关于肾移植或高钙血症并发暴发性肺钙化的报道。对此类病变进行影像学识别对于纠正钙代谢紊乱很重要。否则，该病症可能会逐渐发展并导致呼吸衰竭，危及生命。
