各种胆汁盐对肠道细菌β-葡萄糖醛酸酶活性的影响。

Influence of various bile salts on beta-glucuronidase activity of intestinal bacteria.

作者信息

Fujisawa T, Mori M

机构信息

Kanagawa Prefectural Public Health Laboratory, Yokohama, Japan.

出版信息

Lett Appl Microbiol. 1997 Aug;25(2):95-7. doi: 10.1046/j.1472-765x.1997.00180.x.

DOI:10.1046/j.1472-765x.1997.00180.x

PMID:9281856

Abstract

While the decrease of the beta-glucuronidase activity of sonicated cells of Clostridium perfringens and Escherichia coli was obvious for sodium deoxycholate (DC), it was not so obvious for other bile salts (sodium glycocholate and sodium cholate). The enzyme activity of intact cells of these bacteria was significantly enhanced by the presence of DC, but not by the other bile salts in the buffer. These results suggest that the permeability of the bacterial cells is increased more by the presence of DC than by other bile salts.

摘要

虽然脱氧胆酸钠（DC）能显著降低产气荚膜梭菌和大肠杆菌超声破碎细胞的β-葡萄糖醛酸酶活性，但对其他胆盐（甘氨胆酸钠和胆酸钠）而言，这种降低并不明显。在缓冲液中，DC能显著增强这些细菌完整细胞的酶活性，但其他胆盐则不能。这些结果表明，DC比其他胆盐更能增加细菌细胞的通透性。