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左心室动脉瘤切除术;两种技术的比较;早期和晚期结果

Left ventricular aneurysmectomy; comparison between two techniques; early and late results.

作者信息

Sinatra R, Macrina F, Braccio M, Melina G, Luzi G, Ruvolo G, Marino B

机构信息

Institute of Cardiac Surgery, Policlinico Umberto I, University of Rome La Sapienza, Italy.

出版信息

Eur J Cardiothorac Surg. 1997 Aug;12(2):291-7. doi: 10.1016/s1010-7940(97)00121-8.

Abstract

OBJECTIVE

The aim of the present study was to evaluate early and late results of two different surgical techniques for left ventricular aneurysms repair. The conventional aneurysmectomy and direct closure of the ventricular wall and the endoventricular patch plasty.

METHODS

We retrospectively reviewed 118 patients operated on for postinfarction left ventricular aneurysm from 1981 to 1994. Eighty-seven patients (Group A) were operated upon between 1981 and 1991 with the conventional technique and 31 patients (Group B) between 1992 and 1994 with the endoventricular patch plasty technique. Preoperative clinical, hemodynamic and echocardiographic evaluation with operative procedures and early postoperative results of all patients are reported. We also analyzed results of late clinical and echocardiographic controls of 34 patients of Group A and all patients of Group B after a mean follow-up of 42 and 28 months, respectively.

RESULTS

Mean number of by-pass grafts was 1.9 in Group A and 2.6 in Group B (P = 0.01). The left anterior descending coronary artery was revascularized in 27 patients of Group A (34.6%) and 26 of Group B (89.7%) (P < 0.001); the left internal mammary artery was used in seven patients of Group A (8.9%) and 24 of Group B (82.8%) (P < 0.001). Hospital mortality in Group A was 10.3% (9/87), in Group B there was no hospital mortality (P > 0.05). Thirty-two patients of Group A (36.8%) and 3 of Group B (9.7%) suffered of low cardiac output syndrome (P = 0.01). At late control, improvements observed in NYHA and CCS classes, left ventricular ejection fraction (all P < 0.001 in both groups versus preoperative values) and left ventricular end-diastolic diameter (P > 0.05 in Group A and P < 0.001 in Group B) proved to be statistically higher in patients of Group B.

CONCLUSIONS

Endoventricular patch plasty associated with a complete myocardial revascularization, in particular of the anterior descending coronary, and a larger use of the internal mammary artery, permits, by means of reconstruction of the left ventricular geometry, a better outcome for patients undergoing left ventricular aneurysmectomy.

摘要

目的

本研究旨在评估两种不同手术技术修复左心室室壁瘤的早期和晚期结果。这两种技术分别是传统的室壁瘤切除术及心室壁直接缝合术和心室内补片成形术。

方法

我们回顾性分析了1981年至1994年间因心肌梗死后左心室室壁瘤接受手术治疗的118例患者。87例患者(A组)于1981年至1991年间采用传统技术进行手术,31例患者(B组)于1992年至1994年间采用心室内补片成形术。报告了所有患者的术前临床、血流动力学和超声心动图评估结果以及手术过程和术后早期结果。我们还分别对A组的34例患者和B组的所有患者进行了平均42个月和28个月的晚期临床和超声心动图随访分析。

结果

A组平均搭桥支数为1.9支而B组为2.6支(P = 0.01)。A组27例患者(34.6%)和B组26例患者(89.7%)的左前降支冠状动脉实现了血运重建(P < 0.001);A组7例患者(8.9%)和B组24例患者(82.8%)使用了左乳内动脉(P < 0.001)。A组的医院死亡率为10.3%(9/87),B组无医院死亡病例(P > 0.05)。A组32例患者(36.8%)和B组3例患者(9.7%)出现低心排血量综合征(P = 0.01)。在晚期随访时,B组患者在纽约心脏协会(NYHA)心功能分级、加拿大心血管学会(CCS)分级、左心室射血分数(两组与术前值相比均P < 0.001)和左心室舒张末期内径方面(A组P > 0.05,B组P < 0.001)的改善在统计学上更为显著。

结论

心室内补片成形术联合完全心肌血运重建,尤其是左前降支冠状动脉的血运重建,以及更多地使用乳内动脉,通过重建左心室几何形态,能使接受左心室室壁瘤切除术的患者获得更好的预后。

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