Ceniceros Rozalén I, Gastaldo Simeón R, Cabadés O'Callaghan A, Cebrián Doménech J
Servicio de Medicina Intensiva, Hospital Universitario La Fe, Valencia.
Med Clin (Barc). 1997 Jun 28;109(5):171-4.
To assess the effect of female gender on mortality after acute myocardial infarction (AMI), we studied a cohort of 876 consecutive patients, being women 253 of them (28.8%), admitted to the intensive Care Unit (ICU) because of a first AMI, from September 1992 to October 1995.
We compared the clinical characteristics, the complications and the treatment in both sexes. We estimated the relative risk using logistic regression, being the sex, the independent variable and dependent variables age, history of hypertension and diabetes, AMI location and thrombolytic treatment.
The age was higher and the history of hypertension and diabetes more frequent. The AMI location was less often inferior. Women received fibrinolytic treatment less frequently in women than in men. The mortality in the ICU was higher in the women (29.2 vs. 13.5% in the men) and, after adjusting for the previous factors the relative risk was 1.51 (95% confidence internal of 1.01-2.26).
In the population studied, the female gender is an independent risk factor for early mortality in the AMI.
为评估女性性别对急性心肌梗死（AMI）后死亡率的影响，我们研究了1992年9月至1995年10月期间因首次AMI入住重症监护病房（ICU）的876例连续患者队列，其中女性253例（28.8%）。
我们比较了两性的临床特征、并发症及治疗情况。我们使用逻辑回归估计相对风险，以性别作为自变量，年龄、高血压和糖尿病病史、AMI部位及溶栓治疗作为因变量。
女性年龄较大，高血压和糖尿病病史更常见。AMI部位较少为下壁。女性接受纤维蛋白溶解治疗的频率低于男性。女性在ICU的死亡率较高（女性为29.2%，男性为13.5%），在对上述因素进行校正后，相对风险为1.51（95%置信区间为1.01 - 2.26）。
在所研究的人群中，女性性别是AMI早期死亡的独立危险因素。
