Linke R, Tatsch K, Münzing W, Voderholzer W, Schindlbeck N, Hahn K
Klinik und Poliklinik für Nuklearmedizin, Ludwig-Maximilians-Universität, München, Deutschland.
Nuklearmedizin. 1997 Jun;36(4):131-6.
Patients with various disorders of gastric function were studied with radiolabeled test meals of different consistency to elaborate the effect of ingested media on gastric peristalsis and emptying.
In 12 patients parameters of gastric function were intraindividually compared after ingestion of a semiliquid and a solid test meal. In addition to the standard evaluation derived from time activity curves condensed images were established from two fixed time intervals (early and late period). These images were used to evaluate the amplitude and frequency of gastric contractions using Fourier analysis.
As expected gastric emptying was influenced by the consistency of the test meal. Mean emptying rates for the solid meal were significant lower than those for the semiliquid one (p < 0.01). The amplitude and frequency of gastric contractions, however, did not depend on the consistency of the test meal. Within the course of the examination contraction amplitudes significantly increased (p < 0.05) from the early to the late period using both, solid as well as semiliquid test meals. The frequency of gastric contractions remained unchanged.
As shown by an intraindividual data comparison amplitude and frequency of gastric contractions seem to be independent of the consistency of ingested test meals whereas gastric emptying is significantly influenced by the administered media. Semiliquid meals offer advantages with respect to the shorter examination time and simpler preparation and therefore may be preferred for routine use. Since amplitudes seem to vary within the observation period standardized acquisition protocols are recommended for the evaluation of this parameter.
使用不同稠度的放射性标记试验餐对各种胃功能紊乱患者进行研究,以阐明摄入介质对胃蠕动和排空的影响。
对12例患者在摄入半流质和固体试验餐后分别比较胃功能参数。除了从时间-活性曲线得出的标准评估外,还从两个固定时间间隔(早期和晚期)建立了浓缩图像。这些图像用于通过傅里叶分析评估胃收缩的幅度和频率。
正如预期的那样,胃排空受试验餐稠度的影响。固体餐的平均排空率显著低于半流质餐(p<0.01)。然而,胃收缩的幅度和频率并不取决于试验餐的稠度。在检查过程中,无论是固体试验餐还是半流质试验餐,从早期到晚期收缩幅度均显著增加(p<0.05)。胃收缩频率保持不变。
个体内数据比较显示,胃收缩的幅度和频率似乎与摄入试验餐的稠度无关,而胃排空受给药介质的显著影响。半流质餐在检查时间较短和准备更简单方面具有优势,因此可能更适合常规使用。由于在观察期内幅度似乎有所变化,建议采用标准化采集方案来评估该参数。