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女性尿失禁的临床预测因素

Clinical predictors of urinary incontinence in women.

作者信息

Cundiff G W, Harris R L, Coates K W, Bump R C

机构信息

Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC 27710, USA.

出版信息

Am J Obstet Gynecol. 1997 Aug;177(2):262-6; discussion 266-7. doi: 10.1016/s0002-9378(97)70185-6.

Abstract

OBJECTIVE

Our purpose was to characterize historic and clinical parameters in incontinent women to determine the predictive value for urodynamic diagnoses.

STUDY DESIGN

The analysis includes 535 consecutive women with final diagnoses of genuine stress incontinence, detrusor instability, or both. Evaluations included a standardized history, examination, urinary diary, quantitation test, and urodynamics. The analysis used one-way analysis of variance, chi 2 analysis with Yates' correction, and Fisher's exact test.

RESULTS

A total of 351 (66%) women were diagnosed with genuine stress incontinence, 102 (19%) with detrusor instability, and 82 (15%) with both. Half had symptoms of both stress incontinence and urge incontinence, of whom only 21% had both genuine stress incontinence and detrusor instability. Fewer than half of women diagnosed with genuine stress incontinence or detrusor instability had just symptoms of stress incontinence or urge incontinence, respectively. Evaluation of historic, examination, and urinary diary data for their influences on the predictive value of pure stress incontinence or urge incontinence revealed statistical differences for urethral hypermobility, estrogen deficiency, and incontinent episodes, yet they were not clinically practical predictors.

CONCLUSIONS

Pure symptoms identify fewer than half of patients with pure genuine stress incontinence or detrusor instability; historic and clinical parameters do not improve the sensitivity of these symptoms.

摘要

目的

我们的目的是描述尿失禁女性的病史和临床参数,以确定其对尿动力学诊断的预测价值。

研究设计

该分析纳入了535例最终诊断为真性压力性尿失禁、逼尿肌不稳定或两者皆有的连续女性患者。评估包括标准化病史、检查、排尿日记、定量试验和尿动力学检查。分析采用单因素方差分析、校正Yates法的卡方分析和Fisher精确检验。

结果

共有351例(66%)女性被诊断为真性压力性尿失禁,102例(19%)为逼尿肌不稳定,82例(15%)两者皆有。半数患者同时有压力性尿失禁和急迫性尿失禁症状,其中只有21%同时患有真性压力性尿失禁和逼尿肌不稳定。被诊断为真性压力性尿失禁或逼尿肌不稳定的女性中,分别只有不到半数仅有压力性尿失禁或急迫性尿失禁症状。对病史、检查和排尿日记数据对单纯压力性尿失禁或急迫性尿失禁预测价值的影响进行评估,结果显示尿道活动过度、雌激素缺乏和尿失禁发作次数存在统计学差异,但它们并非临床上实用的预测指标。

结论

单纯症状只能识别不到半数的单纯真性压力性尿失禁或逼尿肌不稳定患者;病史和临床参数并不能提高这些症状的敏感性。

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