DeWeese J A, Rob C G
Surgery. 1977 Dec;82(6):755-84.
The status of 103 patients and their 113 autogenous venous femoropopliteal bypass grafts exactly 5 years after operation was presented previously. A 10 year follow-up now is possible. The mortality rate at 5 years was 48% (50 of 103) and at 10 years was 73% (75 of 103). Myocardial infarction was considered to be the cause of death of 36% of the 103 patients. The actual graft patency rate for survivors at 5 years was 59% (35 of 59) and at 10 years was 38% (11 of 29). Utilizing the same date, late graft patency rates of 45%, 58%, and 58% would have been calculated or predicted by other methods of reporting. Of 46 extremities operated on for claudication, 22 patients were alive and 45% of grafts (10 of 22) were patent 10 years later. Of patients with a total of 67 extremities operated on for rest pain or gangrene, only seven patients were alive and 14% (one of seven) of the grafts patent. Patency rates at 10 years of short grafts were 43% (nine of 21) and of long grafts 25% (two of eight). Extremities with good runoff had patency rates of 41% (nine of 22) at 10 years and those with poor runoff had patency rates of 29% (two of seven). Arteriograms demonstrated atherosclerotic changes in one of 18 grafts at 5 years and in two of eight grafts at 10 years. This study provides more facts for answering the questions of patients regarding long-term prognosis following their arterial reconstruction. It is important to analyze carefully any report in which a comparison of patency rates is suggested or invited.
先前报告了103例患者及其113条自体静脉股腘动脉搭桥移植物术后整整5年的情况。现在可以进行10年随访。5年时的死亡率为48%(103例中的50例),10年时为73%(103例中的75例)。心肌梗死被认为是103例患者中36%的死亡原因。存活患者5年时移植物实际通畅率为59%(59例中的35例),10年时为38%(29例中的11例)。利用相同数据,通过其他报告方法计算或预测的晚期移植物通畅率分别为45%、58%和58%。46例因间歇性跛行接受手术的肢体中,22例患者存活,10年后45%的移植物(22例中的10例)通畅。67例因静息痛或坏疽接受手术的患者中,仅7例患者存活,14%的移植物(7例中的1例)通畅。短移植物10年时的通畅率为43%(21例中的9例),长移植物为25%(8例中的2例)。流出道良好的肢体10年时通畅率为41%(22例中的9例),流出道差的肢体通畅率为29%(7例中的2例)。动脉造影显示,5年时18例移植物中有1例出现动脉粥样硬化改变,10年时8例移植物中有2例出现。本研究为回答患者关于动脉重建术后长期预后的问题提供了更多事实依据。仔细分析任何提出或要求比较通畅率的报告很重要。