Chua J J, Tan P K, Seow W T
Department of Surgery Tan Tock Seng Hospital, Singapore.
Singapore Med J. 1997 Jun;38(6):266-7.
The incidence of clinical leptomeningeal metastases from non-neurologic solid tumour is generally increasing as a result of better survival of systemic cancer with chemotherapy. Their presentation varies according to the neurological involvement. A case of leptomeningeal metastasis from an unknown primary source presenting with urinary incontinence as the sole complaint is reported. While urinary incontinence is common in the community and is often functional, neurogenic causes must also be considered. Urodynamic study and electrophysiological assessment are useful investigations in the exclusion of a neurogenic cause. An MRI of the spine will be required to define any anatomic lesion.
由于化疗使系统性癌症患者的生存率提高,非神经系统实体瘤所致临床软脑膜转移的发生率总体呈上升趋势。其临床表现因神经受累情况而异。本文报告了一例原发灶不明的软脑膜转移病例,该病例以尿失禁为唯一主诉。虽然尿失禁在普通人群中很常见且往往是功能性的,但也必须考虑神经源性病因。尿动力学研究和电生理评估是排除神经源性病因的有用检查方法。需要进行脊柱磁共振成像(MRI)以明确任何解剖学病变。