Köster H, Liebermann B, Reuter G
Z Allg Mikrobiol. 1977;17(6):433-6. doi: 10.1002/jobm.3630170604.
During application of D-glucose-u-14C paromomycine II is higher labelled and shows a different dependence on the application time than paromomycine I, which is isomer at the paromose part. For the two paromose isomeres different rates of synthesis are supposed that change nonproportionally to each other. The distribution of radioactivity in paromomycine I shows that there is no fragmentation of the glucose chain during the biosynthesis of glucosamine, ribose, and paromose I. As to the 2-deoxystreptamine the result has not been ascertained.
在应用D-葡萄糖-u-14C时，巴龙霉素II的标记程度更高，并且与巴龙霉素I对应用时间的依赖性不同，巴龙霉素I是副糖部分的异构体。对于这两种副糖异构体，推测其合成速率不同，且彼此不成比例地变化。巴龙霉素I中的放射性分布表明，在氨基葡萄糖、核糖和副糖I的生物合成过程中，葡萄糖链没有断裂。关于2-脱氧链霉胺，尚未确定结果。
