Newell A M, Deckert J J
St. John's Mercy Medical Center, St. Louis, Missouri, USA.
Am Fam Physician. 1997 Sep 15;56(4):1103-8.
Although ischemic colitis is often considered a condition of elderly persons or persons with vascular disease, it also occurs in healthy adults under age 60. While some patients may have gangrenous forms of ischemic colitis, others may have a benign, self-limited form of the disorder. In these cases, the condition is termed "transient ischemic colitis." This disorder should be included in the differential diagnosis in patients presenting with abdominal pain and hematochezia or bloody diarrhea. Estrogen or oral contraceptive therapy is associated with transient ischemic colitis, so its use should further raise suspicion. The effectiveness of discontinuation of estrogen therapy is controversial, but this measure should be considered. Conservative management includes repeated careful assessment, pain management and fluid replacement. Complications are rare and the prognosis is excellent. Occasionally, patients have recurrences.
尽管缺血性结肠炎通常被认为是老年人或患有血管疾病者的病症,但它也会发生在60岁以下的健康成年人身上。一些患者可能患有坏疽型缺血性结肠炎,而另一些患者可能患有良性、自限性的该疾病形式。在这些情况下,这种病症被称为“短暂性缺血性结肠炎”。对于出现腹痛和便血或血性腹泻的患者,鉴别诊断应包括这种病症。雌激素或口服避孕药治疗与短暂性缺血性结肠炎有关,因此使用这些药物应进一步提高怀疑度。停用雌激素治疗的有效性存在争议,但应考虑采取这一措施。保守治疗包括反复仔细评估、疼痛管理和补液。并发症罕见,预后良好。偶尔,患者会复发。