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因嗅吸橡胶胶水导致的正己烷神经病变。

n-Hexane neuropathy due to rubber cement sniffing.

作者信息

Smith A G, Albers J W

机构信息

Department of Neurology, University of Michigan Medical Center, Ann Arbor 48109, USA.

出版信息

Muscle Nerve. 1997 Nov;20(11):1445-50. doi: 10.1002/(sici)1097-4598(199711)20:11<1445::aid-mus13>3.0.co;2-0.

Abstract

n-Hexane neuropathy has been described after glue sniffing and industrial exposure. Onset may be subacute and reminiscent of Guillain-Barré syndrome. Although the primary pathology is axonal, electrophysiologic evaluation is frequently most remarkable for conduction slowing. We describe a patient with a severe subacute neuropathy following n-hexane exposure via glue sniffing. Although symptoms worsened after termination of exposure ("coasting"), strength gradually improved to near normal. Sources of toxic exposure should be sought in all patients with subacute demyelinating neuropathies.

摘要

吸入胶水和职业接触正己烷后可出现正己烷神经病。起病可能为亚急性,类似吉兰 - 巴雷综合征。虽然主要病理改变为轴索性,但电生理评估常以传导速度减慢最为显著。我们描述了一名因吸入胶水接触正己烷后出现严重亚急性神经病的患者。尽管接触终止后症状加重(“滑行”现象),但肌力逐渐改善至接近正常。对于所有亚急性脱髓鞘性神经病患者,均应寻找有毒物质接触源。

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