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慢性丘脑损伤鸽子的基础及应激诱导的肾上腺皮质活动

Basal and stress-induced adrenal cortical activities in the chronic thalamic pigeon.

作者信息

Baylé J D

出版信息

Neuroendocrinology. 1976;20(1):14-20. doi: 10.1159/000122462.

DOI:10.1159/000122462
PMID:934423
Abstract

The plasma corticosterone level was determined in chronic thalamic pigeons. Basal resting adrenocortical activity did not show any diurnal variation and kept a steady intermediate level. The peak and nadir in the morning and in the evening were completely suppressed. Neurogenic stress (restraint) resulted in a sharp increase in the plasma corticosterone concentration 15 min after immobilization. This response was as important in magnitude (three-fold the resting level) in thalamic pigeons as in intact birds. These results can be compared with data obtained after complete or partial deafferentation of the hypothalamus, and after hippocampal or archistriate lesions, and are discussed in terms of sleep-walking alternation in these various experimentally-prepared pigeons.

摘要

测定了慢性丘脑损伤鸽子的血浆皮质酮水平。基础静息肾上腺皮质活动未表现出任何昼夜变化,维持在稳定的中等水平。早晚的峰值和谷值完全被抑制。神经源性应激(束缚)导致固定后15分钟血浆皮质酮浓度急剧升高。这种反应在丘脑损伤鸽子中的幅度(是静息水平的三倍)与完整鸟类中的一样重要。这些结果可与下丘脑完全或部分去传入神经后以及海马或古纹状体损伤后获得的数据进行比较,并根据这些不同实验制备鸽子的梦游交替情况进行讨论。

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