Potter J D
Cancer Prevention Research Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
IARC Sci Publ. 1997(142):31-7.
Standard epidemiological study designs are well suited to answering questions involving the collection of biological samples. However, different designs are better suited--both for design and logistic reasons--to different questions. The strengths and weaknesses of each design are discussed in relation to markers of exposure, susceptibility and early outcome, and to markers used to classify cancers into biologically defined subsets.
标准的流行病学研究设计非常适合回答涉及生物样本收集的问题。然而，出于设计和后勤方面的原因，不同的设计更适合不同的问题。将针对暴露、易感性和早期结果的标志物，以及用于将癌症分类为生物学定义亚组的标志物，讨论每种设计的优缺点。
