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利用Tc-99m标记红细胞进行肝血管瘤成像的早期动态单光子发射计算机断层扫描采集。

Early dynamic SPECT acquisition for the imaging of hepatic hemangiomas utilizing Tc-99m labeled red blood cells.

作者信息

Siegel A, Mazurek R

机构信息

Department of Radiology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03755, USA.

出版信息

Clin Nucl Med. 1997 Nov;22(11):745-8. doi: 10.1097/00003072-199711000-00001.

Abstract

PURPOSE

To determine whether rapid, dynamic SPECT imaging with Tc-99m labeled red blood cells was technically feasible and of value in the detection of cavernous hemangiomas of the liver.

MATERIALS AND METHODS

The acquisition protocol for Tc-99m labeled red blood cell imaging of hepatic hemangiomas was modified with six sequential 3-minute SPECT images replacing the planar flow phase. Delayed 20-minute SPECT of the liver was then performed 2 hours later.

RESULTS

The authors present examples of pathologically proven positive and negative cases and retrospectively review their patient series. Examination of 19 patients with 41 lesions revealed no evidence of a false-positive examination results and only one false-negative result. Only one lesion seen to be positive with a 2-hour delayed study was not seen within 18 minutes. Lesions as small as 1.0 cm could be detected with a 3-minute SPECT.

CONCLUSIONS

Rapid, dynamic early SPECT hemangioma imaging is feasible, provides images with relatively good quality, and can replace the planar flow phase.

摘要

目的

确定使用锝-99m标记红细胞进行快速动态单光子发射计算机断层扫描(SPECT)成像在检测肝脏海绵状血管瘤方面在技术上是否可行以及是否有价值。

材料与方法

对肝脏血管瘤的锝-99m标记红细胞成像采集方案进行了修改,用六个连续的3分钟SPECT图像取代平面血流相。然后在2小时后进行肝脏延迟20分钟的SPECT检查。

结果

作者展示了经病理证实的阳性和阴性病例示例,并回顾性分析了他们的患者系列。对19例患者的41个病灶进行检查,未发现假阳性检查结果的证据,仅出现1例假阴性结果。在2小时延迟研究中显示为阳性的病灶,在18分钟内未被发现。3分钟SPECT可检测到小至1.0厘米的病灶。

结论

快速动态早期SPECT血管瘤成像可行,能提供质量相对较好的图像,且可取代平面血流相。

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