对从日本急性结膜炎患者中分离出的4型腺病毒毒株进行的基因组分析。

Genome analysis of adenovirus type 4 strains isolated from acute conjunctivitis in Japan.

作者信息

Tsuzuki-Wang L, Aoki K, Isobe K, Shiao S, Toba K, Kobayashi N, Noguchi Y, Ohno S

机构信息

Department of Ophthalmology, Yokohama City University School of Medicine, Yokohama, Japan.

出版信息

Jpn J Ophthalmol. 1997 Sep-Oct;41(5):308-11. doi: 10.1016/s0021-5155(97)00067-1.

DOI:10.1016/s0021-5155(97)00067-1

PMID:9363559

Abstract

Strains of adenovirus type 4 (Ad4) isolated from patients with acute conjunctivitis were studied by DNA restriction analysis. The strains were isolated between July and December 1990 in Japan. All 63 isolates of Ad4 were identified as the genome type Ad4a. This study showed that the same Ad4 genome type, Ad4a, caused acute viral conjunctivitis, even in different areas of Japan.

摘要

通过DNA限制性分析对从急性结膜炎患者中分离出的4型腺病毒（Ad4）毒株进行了研究。这些毒株于1990年7月至12月间在日本分离得到。所有63株Ad4分离株均被鉴定为Ad4a基因组类型。该研究表明，即使在日本的不同地区，相同的Ad4基因组类型Ad4a也会引发急性病毒性结膜炎。