Hanyu S, Ito U, Hakamata Y, Nakano I
Department of Neurology, Jichi Medical School, Tochigi, Japan.
Brain Res. 1997 Aug 29;767(1):154-7. doi: 10.1016/s0006-8993(97)00726-9.
A study was carried out of the distribution and density of the neurons remaining in the gerbil cerebral cortex following two 10-min periods of ischemia at either 3-, 5- or 48-h intervals. As the interval between the periods of ischemia increased, the ischemic injury was reduced from severe to milder infarction, and further from more to less intense disseminated selective neuronal necrosis. This model is suitable for studying the mechanisms of transition from selective neuronal necrosis to infarction at the threshold level of infarction.
一项研究对沙鼠大脑皮层在3小时、5小时或48小时间隔的两个10分钟缺血期后剩余神经元的分布和密度进行了研究。随着缺血期之间间隔的增加，缺血损伤从严重的梗死减轻为较轻的梗死，进而从更广泛、更强烈的弥漫性选择性神经元坏死减轻为程度较轻的坏死。该模型适用于研究在梗死阈值水平下从选择性神经元坏死向梗死转变的机制。
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