Assignment of the human cardiac/slow skeletal muscle troponin C gene (TNNC1) between D3S3118 and GCT4B10 on the short arm of chromosome 3 by somatic cell hybrid analysis.
作者信息
Townsend P J, Yacoub M H, Barton P J
机构信息
Imperial College School of Medicine, National Heart and Lung Institute, London.
出版信息
Ann Hum Genet. 1997 Jul;61(Pt 4):375-7. doi: 10.1046/j.1469-1809.1997.6140375.x.
Abstract
We have determined the chromosomal location of the human cardiac/slow skeletal muscle troponin C gene (TNNC1) to the short arm of chromosome 3 using somatic cell hybrids. PCR-based analysis of a 'monochromosomal' hybrid panel identified the presence of the TNNC1 gene on human chromosome 3 and subsequent analysis of the Genebridge4 radiation hybrid panel located the gene between D3S3118 (7.3cR) and GCT4B10 (4.2cR) with a lod score of > 3.0.
摘要
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