Sakai T, Shimada M, Ishizaki T, Nakai T
Fukui General Hospital, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1997 Aug;35(8):894-9.
In a 65-year-old man with chronic obstructive pulmonary disease and acute respiratory failure, bi-level positive airway pressure device (BiPAP) was used as part of weaning from mechanical ventilation. As an outpatient, he had had dyspnea of grade V (Hugh-Jones) and was hypercapnic (PaCO2 of 70 torr) and hypoxemic (PaO2 of 60 torr), while he was receiving oxygen at 2 L/min via nasal cannula. Acute respiratory failure developed due to pneumonia, and mechanical ventilation was begun. However, he could not be weaned with a standard weaning technique (T-piece). On the fifth day of mechanical ventilation, he was extubated and treatment with BiPAP was begun. He did not complain of dyspnea even though PaCO2 did not decrease, which indicates that BiPAP reduced the work of breathing. Use of BiPAP might make reintubation unnecessary when acute ventilatory failure develops soon after extubation in patients with COPD.
在一名患有慢性阻塞性肺疾病且发生急性呼吸衰竭的65岁男性患者中,双水平气道正压通气设备(BiPAP)被用作机械通气撤机的一部分。作为门诊患者,他曾有V级(Hugh-Jones分级)呼吸困难,存在高碳酸血症(动脉血二氧化碳分压[PaCO2]为70托)和低氧血症(动脉血氧分压[PaO2]为60托),当时他正通过鼻导管以2升/分钟的流量吸氧。因肺炎发生急性呼吸衰竭,遂开始机械通气。然而,采用标准撤机技术(T形管)他无法撤机。在机械通气的第5天,他拔除气管插管并开始使用BiPAP治疗。尽管PaCO2未降低,但他并未诉说呼吸困难,这表明BiPAP减轻了呼吸功。对于慢性阻塞性肺疾病患者,在拔管后不久发生急性通气衰竭时,使用BiPAP可能无需再次插管。