Diazepam-mediated inhibition of human immunodeficiency virus type 1 expression in human brain cells.
作者信息
Lokensgard J R, Gekker G, Hu S, Arthur A F, Chao C C, Peterson P K
机构信息
Institute for Brain and Immune Disorders, Minneapolis Medical Research Foundation, Minnesota 55404, USA.
出版信息
Antimicrob Agents Chemother. 1997 Nov;41(11):2566-9. doi: 10.1128/AAC.41.11.2566.
Abstract
Treatment of acutely infected human brain cell and enriched microglial cell cultures with diazepam inhibited human immunodeficiency virus type 1 (HIV-1) p24 antigen expression. Similarly, diazepam suppressed HIV-1 expression in chronically infected promonocytic (U1) cells and acutely infected monocyte-derived macrophages, and this antiviral activity was associated with decreased activation of nuclear factor kappa B.
摘要
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1
Proinflammatory cytokines inhibit HIV-1(SF162) expression in acutely infected human brain cell cultures.
J Immunol. 1997 Mar 1;158(5):2449-55.
2
CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia.
Nature. 1997 Feb 13;385(6617):645-9. doi: 10.1038/385645a0.
3
Characterization of peripheral benzodiazepine type sites in a cultured murine BV-2 microglial cell line.
Glia. 1996 Jan;16(1):65-70. doi: 10.1002/(SICI)1098-1136(199601)16:1<65::AID-GLIA7>3.0.CO;2-A.
4
Genetic toxicology of four commonly used benzodiazepines: a review.
Mutat Res. 1996 Jun;340(2-3):93-108. doi: 10.1016/s0165-1110(96)90042-1.
5
Permanent occupancy of the human immunodeficiency virus type 1 enhancer by NF-kappa B is needed for persistent viral replication in monocytes.
J Virol. 1996 May;70(5):2930-8. doi: 10.1128/JVI.70.5.2930-2938.1996.
6
Chronic human immunodeficiency virus type 1 infection stimulates distinct NF-kappa B/rel DNA binding activities in myelomonoblastic cells.
J Virol. 1993 Sep;67(9):5235-46. doi: 10.1128/JVI.67.9.5235-5246.1993.
7
Distribution profile and properties of peripheral-type benzodiazepine receptors on human hemopoietic cells.
Life Sci. 1993;52(1):107-18. doi: 10.1016/0024-3205(93)90293-c.
8
9
Human microglial cell defense against Toxoplasma gondii. The role of cytokines.
J Immunol. 1994 Feb 1;152(3):1246-52.
10
Characterization of the peripheral-type benzodiazepine receptors in cultured astrocytes: evidence for multiplicity.
Glia. 1993 Nov;9(3):211-8. doi: 10.1002/glia.440090306.
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