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羟基磷灰石涂层植入物。年轻患者及股骨头缺血性坏死患者的全髋关节置换术。

Hydroxyapatite coated implants. Total hip arthroplasty in the young patient and patients with avascular necrosis.

作者信息

D'Antonio J A, Capello W N, Manley M T, Feinberg J

机构信息

M.H. & D. Orthopedics, Moon Township, PA 15108, USA.

出版信息

Clin Orthop Relat Res. 1997 Nov(344):124-38.

PMID:9372765
Abstract

Two high risk groups for total hip arthroplasty, 136 patients (155 hips) younger than 50 years of age (average age, 38 years) and 44 patients (53 hips) with the diagnosis of avascular necrosis, have a minimum followup of 5 years and a mean followup of 6.8 years. The average Harris Hip Score at last followup totaled 93 and 90, respectively, and thigh pain was reported in 1.3% and 3.8%, respectively. All patients in both groups received the same hydroxyapatite coated femoral stem and the mechanical failure was 0%. No stem was revised for aseptic loosening, 100% of stems were bony stable by radiographic criteria, new bone formation was progressive about the femoral stem, and 0% endosteal lysis was found. The acetabular components had a mechanical failure rate of 10% and 7.5%, respectively, without osteolysis, and an additional 7% and 7.5% failure as a direct result of progressive osteolysis. The results with the porous press fit and hydroxyapatite threaded sockets were far superior to that of the smooth hydroxyapatite press fit sockets and socket failure was associated with thin polyethylene liners and the use of 32-mm head diameters. These findings show a high success rate with a nonporous hydroxyapatite coated titanium femoral stem. However, hydroxyapatite on a smooth acetabular component yielded less predictable results indicating that for long term fixation of the acetabulum an interlock of bone is preferred.

摘要

两组全髋关节置换术的高风险患者,136例(155髋)年龄小于50岁(平均年龄38岁),44例(53髋)诊断为缺血性坏死,进行了至少5年的随访,平均随访6.8年。末次随访时,两组患者的平均Harris髋关节评分分别为93分和90分,大腿疼痛发生率分别为1.3%和3.8%。两组所有患者均接受相同的羟基磷灰石涂层股骨柄,机械故障率为0%。无股骨柄因无菌性松动而翻修,根据影像学标准100%的股骨柄骨稳定,股骨柄周围新骨形成进展,骨内膜溶解率为0%。髋臼假体的机械故障率分别为10%和7.5%,无骨溶解,另外分别有7%和7.5%的失败是由进行性骨溶解直接导致的。多孔压配和羟基磷灰石螺纹髋臼杯的结果远优于光滑羟基磷灰石压配髋臼杯,髋臼杯失败与薄聚乙烯内衬和使用32毫米股骨头直径有关。这些发现表明无孔羟基磷灰石涂层钛股骨柄成功率高。然而,光滑髋臼部件上的羟基磷灰石产生的结果不太可预测,这表明对于髋臼的长期固定,骨嵌合更可取。

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