Shlyakhov E, Blancou J, Rubinstein E
Unité des maladies infectieuses, Chaim Sheba Medical Center, Sackler School of Medicine, Tel-Hashomer, Israël.
Rev Sci Tech. 1996 Sep;15(3):853-62.
The authors outline the history of vaccination against anthrax in animals, from the end of the 19th century to the present time. The three main steps in the production of specific vaccines are described in detail: production of vaccines from live, encapsulated bacteria, followed by vaccines from live, unencapsulated bacteria and, finally, subunit vaccines. Advantages and disadvantages of these three types of vaccine, some of which are still in use today, are described and discussed.
作者概述了从19世纪末至今动物炭疽疫苗接种的历史。详细描述了特定疫苗生产的三个主要阶段:从活的、有荚膜的细菌生产疫苗,随后是从活的、无荚膜的细菌生产疫苗,最后是亚单位疫苗。描述并讨论了这三种类型疫苗的优缺点,其中一些至今仍在使用。