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[极低出生体重(500 - 999克)新生儿的存活情况。100例病例回顾]

[Survival of newborn infants with very low birth weight (500-999 g). Review of 100 cases].

作者信息

Guijarro Ponce J A, Manzano Villalba M J, Ferragut Marqués M A, Usandizaga Calparsoro M

机构信息

Servicio de Obstetricia y Ginecología, Hospital Son Dureta Palma de Mallorca.

出版信息

An Esp Pediatr. 1997 Jul;47(1):54-60.

PMID:9382330
Abstract

OBJECTIVE

It is necessary to have thorough knowledge of the survival of extreme low birth weight infants (ELBWI) in order to make it easier for obstetricians, neonatologists and the family to make a decision.

PATIENTS AND METHODS

A revision of the 100 ELBWI in our service between 1988 and 1995, considering live births, those deceased in the same birthing room and those followed until their discharge from the hospital, was performed. The differences between the periods before and after the introduction of pulmonary surfactant in 1992 were analyzed.

RESULTS

The total survival was 37% for those with a birth weight superior to 750 g or 26 weeks gestation. There were 44.2% males and 28.9% females. The total survival improved from 26.1% during 1988-1991 to 46.3% during the period of 1992-1995. During this period (1992-1995), the newborns weighing more than 750 g had a survival rate of 72.4% and for those of 26 weeks gestation it was 73.3%. Those born at 28 weeks gestation and those with 25 weeks of gestation and weighing more than 750 g, the total survival was 63% and the survival rate in the last four years was 75.9%.

CONCLUSIONS

The mortality of the ELBWI descends in similar proportion to the remainder fo the ELBWI. In order to predict the prognosis, it would be necessary to carry out a correct ultrasound estimation of the gestational age and weight. It is necessary to offer a mother in the process of childbirth with a fetus of 28 weeks gestation or with 25 weeks gestation and a fetus with an ultrasound weight greater than 750 g, intrapartum fetal monitoring and to finish by Cesarean section in case of acute fetal distress, as well as intense and immediate neonatal attention as indicated by the index of survival reached in the group mentioned during the later years.

摘要

目的

为便于产科医生、新生儿科医生及患儿家庭做出决策,有必要全面了解极低出生体重儿(ELBWI)的生存情况。

患者与方法

对1988年至1995年间我院收治的100例极低出生体重儿进行回顾性研究,涵盖活产儿、在同一产房死亡的患儿以及住院直至出院的患儿。分析了1992年引入肺表面活性物质前后各时间段的差异。

结果

出生体重超过750克或孕周达26周的患儿总生存率为37%。男性占44.2%,女性占28.9%。总生存率从1988 - 1991年的26.1%提高至1992 - 1995年的46.3%。在此期间(1992 - 1995年),出生体重超过750克的新生儿生存率为72.4%,孕周26周的新生儿生存率为73.3%。孕周28周出生的患儿以及孕周25周且出生体重超过750克的患儿,总生存率为63%,过去四年的生存率为75.9%。

结论

极低出生体重儿的死亡率下降幅度与其他极低出生体重儿相似。为预测预后,有必要对孕周和体重进行准确的超声评估。对于分娩过程中孕周达28周或孕周25周且超声估重超过750克的胎儿,应进行产时胎儿监测,若出现急性胎儿窘迫则行剖宫产终止妊娠,并按照后期该组所达到的生存指标给予积极、及时的新生儿护理。

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