Hiller A, Rosenberg P H
Department of Anaesthesia, Kuusankoski District Hospital, Sairaalamäki, Finland.
Br J Anaesth. 1997 Sep;79(3):301-5. doi: 10.1093/bja/79.3.301.
Several studies have reported transient neurological symptoms after spinal anaesthesia with 5% lignocaine. In order to evaluate the role of concentrated solutions of local anaesthetic in the development of transient neurological symptoms, 200 ASA I or II patients undergoing minor orthopaedic or rectal surgery under spinal anaesthesia were allocated randomly to receive 4% mepivacaine 80 mg or hyperbaric 0.5% bupivacaine 10 mg. All patients were interviewed by an anaesthetist approximately 24 h after spinal anaesthesia, and after 1 week patients were asked to return a written questionnaire. The incidence of transient neurological symptoms consisting of pain in the buttocks or pain radiating symmetrically to the lower extremities differed (P < 0.001) between patients receiving mepivacaine (30%) and those receiving bupivacaine (3%). Hyperbaric 0.5% bupivacaine can be recommended for minor operations on the lower abdomen or lower extremities.
多项研究报道了使用5%利多卡因进行脊髓麻醉后出现的短暂性神经症状。为了评估高浓度局部麻醉剂在短暂性神经症状发生中的作用，将200例接受脊髓麻醉下小型骨科或直肠手术的美国麻醉医师协会（ASA）I级或II级患者随机分配，分别接受80mg的4%甲哌卡因或10mg的高压0.5%布比卡因。脊髓麻醉后约24小时，所有患者均由麻醉师进行访谈，1周后要求患者返回一份书面问卷。接受甲哌卡因的患者（30%）和接受布比卡因的患者（3%）之间，由臀部疼痛或对称放射至下肢的疼痛组成的短暂性神经症状发生率存在差异（P<0.001）。高压0.5%布比卡因可推荐用于下腹部或下肢的小型手术。
