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使用弧形和重力定向补偿器进行全身照射。

Total body irradiation with an arc and a gravity-oriented compensator.

作者信息

Chui C S, Fontenla D P, Mullokandov E, Kapulsky A, Lo Y C, Lo C J

机构信息

Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

出版信息

Int J Radiat Oncol Biol Phys. 1997 Dec 1;39(5):1191-5. doi: 10.1016/s0360-3016(97)00498-7.

Abstract

PURPOSE

To deliver uniform dose distributions for total-body irradiation (TBI) with an arc field and a gravity-oriented compensator. This technique allows the patient to be treated lying on the floor in a small treatment room.

METHODS AND MATERIALS

Through the sweeping motion of the gantry, a continuous arc field can deliver a large field to a patient lying on the floor. The dose profile, however, would not be uniform if no compensator were used, due to the effects of inverse square variation of beam intensity with distance as well as the slanted depth in patient. To solve this problem, a gravity-oriented compensator made of cerrobend alloy was designed. This compensator has a cross-section of an inverted isosceles triangle, with the apex always pointing downward, due to gravity. By properly selecting the thickness of the compensator, the width of the base, and the distance between the pivots to the base, the difference in the path length through the compensator can be made just right to compensate the effects of inverse-square and slanted depth, thus producing a uniform dose profile.

RESULTS

Arc fields with a gravity-oriented compensator were used for 6, 10, 15, and 18 MV photon beams. The arc field can cover a patient with a height up to 180 cm. The field width was chosen from 32 to 40 cm at the machine isocenter. The optimal thickness of the compensator was found to be 2.5 cm, and its base was 25 cm wide. The distance from the pivot points to the flat surface of the compensator proximal to the beam ranges from 13 to 14 cm for different beam energies. The dose uniformity at a depth of 10 cm is within +/-5% for all beam energies used in this study.

CONCLUSIONS

Highly uniform dose profiles for TBI treatments can be delivered with an arc and a gravity-oriented compensator. The proposed technique is simple and versatile. A single compensator can be used for all energies, because the amount of compensation can be adjusted by changing the distance to the pivot and/or the field size.

摘要

目的

利用弧形野和重力定向补偿器实现全身照射(TBI)的均匀剂量分布。该技术允许患者在小型治疗室的地板上接受治疗。

方法和材料

通过机架的扫描运动,连续弧形野可向躺在地板上的患者提供大野照射。然而,如果不使用补偿器,由于射束强度随距离的平方反比变化以及患者体内深度倾斜的影响,剂量分布将不均匀。为解决此问题,设计了一种由铈铍青铜合金制成的重力定向补偿器。由于重力作用,该补偿器的横截面为倒等腰三角形,其顶点始终朝下。通过适当选择补偿器的厚度、底部宽度以及枢轴到基部的距离,可以使穿过补偿器的路径长度差异恰到好处,以补偿平方反比和深度倾斜的影响,从而产生均匀的剂量分布。

结果

将带有重力定向补偿器的弧形野用于6、10、15和18 MV光子束。弧形野可覆盖身高达180 cm的患者。在机器等中心处,野宽度选择为32至40 cm。发现补偿器的最佳厚度为2.5 cm,其底部宽25 cm。对于不同的射束能量,从枢轴点到补偿器靠近射束的平面表面的距离在13至14 cm范围内。在本研究中使用的所有射束能量下,10 cm深度处的剂量均匀性在±5%以内。

结论

使用弧形野和重力定向补偿器可为TBI治疗提供高度均匀的剂量分布。所提出的技术简单且通用。单个补偿器可用于所有能量,因为可以通过改变到枢轴的距离和/或野大小来调整补偿量。

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