Zijlstra F, van 't Hof A W, Liem A L, Hoorntje J C, Suryapranata H, de Boer M J
Department of Cardiology, Hospital De Weezenlanden, Zwolle, The Netherlands.
Heart. 1997 Oct;78(4):333-6. doi: 10.1136/hrt.78.4.333.
To investigate the feasibility of primary coronary angioplasty as a treatment option in patients with acute myocardial infarction after initial diagnosis in a local community hospital.
Referral centre for interventional treatment of coronary artery disease.
During a five year period, 520 candidates for primary coronary angioplasty were treated in our institution, 104 after transfer from a community hospital. The transferred patients and the non-transferred patients (n = 416) were compared with regard to baseline clinical characteristics, time interval from symptom onset to treatment, and clinical outcome at six months.
In this setting, the influence of transportation on total ischaemic time was limited, and there was no difference in clinical outcome between the transferred and the non-transferred patients. Clinical outcome was mainly dependent on the indication for transfer.
Safe and expedient transportation may facilitate the more widespread use of primary angioplasty in patients with acute myocardial infarction. A large randomised multicentre trial is needed to compare the relative merits of intravenous thrombolytic treatment in a local hospital with primary angioplasty after transfer in selected high risk patients with acute myocardial infarction.
探讨在当地社区医院初诊后,直接冠状动脉血管成形术作为急性心肌梗死患者治疗选择的可行性。
冠状动脉疾病介入治疗转诊中心。
在五年期间,我院对520例直接冠状动脉血管成形术候选患者进行了治疗,其中104例是从社区医院转诊而来。对转诊患者和未转诊患者(n = 416)的基线临床特征、症状发作至治疗的时间间隔以及六个月时的临床结局进行了比较。
在此情况下,转运对总缺血时间的影响有限,转诊患者和未转诊患者的临床结局无差异。临床结局主要取决于转诊指征。
安全便捷的转运可能有助于直接血管成形术在急性心肌梗死患者中更广泛地应用。需要进行一项大型随机多中心试验,以比较在当地医院进行静脉溶栓治疗与将选定的急性心肌梗死高危患者转诊后进行直接血管成形术的相对优缺点。