Aslan A, De Donato G, Balyan F R, Falcioni M, Russo A, Taibah A, Sanna M
Gruppo Otologico, Piacenza, Italy.
Otolaryngol Head Neck Surg. 1997 Dec;117(6):580-2. doi: 10.1016/S0194-59989770035-4.
It has long been recognized that sudden hearing loss (SHL) may be a harbinger of vestibular schwannoma (VS). Among 192 VS patients who underwent operation in the Gruppo Otologico, Piacenza, Italy, from April 1987 to October 1995, the charts of 14 (7.3%) cases with a history of SHL were examined. SHL was the first symptom in 8 (4.2%) patients. Eight (57.1%) of 14 VS cases with SHL anamnesis had reported recovery of their previous hearing either totally or partially before establishment of tumor diagnosis. Five (35.7%) cases had recurrent bouts of SHL. SHL was observed less frequently in cases with large tumors (>3 cm). However, the frequency of SHL in patients with small tumors did not differ from that of medium-sized tumors. Awareness about coexistence of SHL and VS, as well as concomitant use of auditory brain stem response and magnetic resonance imaging, is crucial to rule out the diagnosis of VS in a patient with SHL.
长期以来，人们一直认识到突发性听力损失（SHL）可能是前庭神经鞘瘤（VS）的先兆。在1987年4月至1995年10月期间于意大利皮亚琴察的Gruppo Otologico接受手术的192例VS患者中，对14例（7.3%）有SHL病史的病例记录进行了检查。SHL是8例（4.2%）患者的首发症状。14例有SHL既往史的VS病例中，有8例（57.1%）报告在肿瘤诊断确立之前其先前的听力已完全或部分恢复。5例（35.7%）病例有SHL反复发作。在大肿瘤（>3 cm）病例中，SHL的发生率较低。然而，小肿瘤患者中SHL的发生率与中等大小肿瘤患者并无差异。认识到SHL与VS的共存情况，以及同时使用听性脑干反应和磁共振成像，对于排除SHL患者的VS诊断至关重要。
