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老年患者的胆石症:胆道手术所致的发病率和死亡率

Biliary lithiasis in the elderly patient: morbidity and mortality due to biliary surgery.

作者信息

González J J, Sanz L, Grana J L, Bermejo G, Navarrete F, Martinez E

机构信息

Department of Surgery B, Hospital Central University of Oviedo, Spain.

出版信息

Hepatogastroenterology. 1997 Nov-Dec;44(18):1565-8.

PMID:9427023
Abstract

BACKGROUND/AIMS: Diseases of the biliary tract are the most common conditions requiring intra-abdominal surgery in elderly patients. Complications and adverse outcomes of gallstones are more frequent in older people. The present study was undertaken to analyze factors that contributed to overall morbidity and mortality after open cholecystectomy. Laparoscopic surgery and other new techniques were compared with the open method.

METHODOLOGY

We studied retrospectively 76 patients that were 80 years and older. Each patient underwent operation in our unit. 40 patients had fewer than 30 days of clinical history, and 69 patients (90.8%) were emergency admissions. From a clinical point of view, 33 patients (43.4%) had jaundice on arrival and 21 (27.6%) fever. The operative findings included gallbladder wall infection in 46 patients (60.5%) and common bile duct stones in 25. Uni- and multivariate analysis was performed to discriminate variables in mortality and morbidity.

RESULTS

Nine patients (11.8%) died, and 38 had complications in the postoperative period. The main causes of death were pulmonary complications (4) and multisystem organ failure (3). Morbidity was mainly due to wound infection (14), urinary infection (13) and respiratory disease (10). Three variables influenced morbidity: sex (male), cardiovascular disease and jaundice upon admission. In the regression model only cardiovascular disease and jaundice were of independent influence. The mortality rate was associated with pre-operative jaundice.

CONCLUSIONS

Mortality and morbidity are related mainly to preoperative presentation. Jaundice is the main determinant of the outcome.

摘要

背景/目的:胆道疾病是老年患者最常见的需要进行腹腔内手术的病症。胆结石的并发症和不良后果在老年人中更为常见。本研究旨在分析开腹胆囊切除术后导致总体发病率和死亡率的因素。将腹腔镜手术和其他新技术与开放手术方法进行比较。

方法

我们回顾性研究了76例80岁及以上的患者。每位患者均在我们科室接受手术。40例患者的临床病史少于30天,69例患者(90.8%)为急诊入院。从临床角度来看,33例患者(43.4%)入院时出现黄疸,21例患者(27.6%)发热。手术发现包括46例患者(60.5%)胆囊壁感染和25例患者胆总管结石。进行单因素和多因素分析以区分死亡率和发病率的变量。

结果

9例患者(11.8%)死亡,38例患者术后出现并发症。主要死亡原因是肺部并发症(4例)和多系统器官衰竭(3例)。发病率主要归因于伤口感染(14例)、泌尿系统感染(13例)和呼吸道疾病(10例)。三个变量影响发病率:性别(男性)、心血管疾病和入院时黄疸。在回归模型中,只有心血管疾病和黄疸具有独立影响。死亡率与术前黄疸有关。

结论

死亡率和发病率主要与术前表现有关。黄疸是结果的主要决定因素。

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