Soejima K, Nozaki M, Sasaki K, Takeuchi M, Negishi N
Department of Plastic and Reconstructive Surgery, Tokyo Women's Medical College, Japan.
Burns. 1997 Sep;23(6):501-4. doi: 10.1016/s0305-4179(97)88485-9.
Twelve patients with post-burn contracture were treated using artificial dermis combined with thin split-skin grafting during the period January 1994 to April 1996. Bilayer artificial dermis was grafted onto full thickness open wounds of the skin, after excision of scar contracture tissue. About 3 weeks later, the silicone layer was removed and thin split-skin, 8/1000 in. thick, was grafted onto the newly synthesized dermis-like tissue in the wound bed. Scalp was chosen as the donor site in 11 of the 12 cases. Artificial dermis grafting was undertaken to ensure that morbidity at the donor site could be reduced as much as possible in the treatment of burn deformity. The skin grafts took completely in all cases. Postoperative management was performed in accordance with conventional skin grafting. Postoperative contraction or hypertrophic scar was observed in three cases, but a soft, favorable quality was obtained in the other nine cases. Treatment of burn deformity with artificial dermis may be beneficial in selected cases.
1994年1月至1996年4月期间，对12例烧伤后挛缩患者采用人工真皮联合薄断层皮片移植进行治疗。在切除瘢痕挛缩组织后，将双层人工真皮移植到皮肤全层开放性伤口上。约3周后，去除硅胶层，将厚度为8/1000英寸的薄断层皮片移植到创面床新合成的真皮样组织上。12例中有11例选择头皮作为供皮区。进行人工真皮移植以确保在烧伤畸形治疗中尽可能降低供皮区的发病率。所有病例皮片均完全成活。术后按照传统植皮方法进行处理。3例出现术后挛缩或增生性瘢痕，但其他9例获得了柔软、良好的效果。在某些特定病例中，用人工真皮治疗烧伤畸形可能有益。
