Czeizel A E, Göblyös P
Department of Human Genetics and Teratology, National Institute of Public Health-WHO Collaborating Centre for the Community Control of Hereditary Diseases, Budapest, Hungary.
J Med Genet. 1997 Dec;34(12):1033-4. doi: 10.1136/jmg.34.12.1033.
A healthy, non-consanguineous couple had a son with complete situs inversus viscerum (including dextrocardia but without other cardiac defects), broad thumbs and big toes, postaxial polydactyly, average intelligence and length proportion of the extremities, and a normal face. The common cause of these defects may have a role in the origin of sidedness and symmetry in morphogenesis.
一对健康、非近亲的夫妇育有一个儿子,该儿子患有完全性内脏反位(包括右位心,但无其他心脏缺陷)、拇指和大脚趾宽阔、轴后多指畸形、智力中等、四肢长度比例正常且面部正常。这些缺陷的常见原因可能在形态发生过程中左右不对称和对称的起源中起作用。